Genomics Clinical Science Advisor

AstraZeneca - Cambridge
05 Aug 2017
02 Sep 2017
Contract Type
Full Time

Position: Genomics Clinical Science Adviser

Location: Cambridge, UK

Salary: Competitive & Excellent Benefits Package

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.

We have an opportunity for outstanding genomics clinical science adviser to join the AstraZeneca Centre for Genomics Research. In this role you'll be critical to the delivery of an unprecedented genomics initiative, involving the analysis of up to 2 million genomes, which will transform drug discovery and development, bringing new innovative medicines to patients faster.

You'll use your skills in genomics clinical science to advise study teams, ethics committees and biobanks from AstraZeneca and major collaborations, to enable sample collection and analysis of up to 2 million genomes. Candidates with a proven record of genomics clinical science delivery in a similar role are particularly encouraged to apply.

AstraZeneca is a science-led, global biopharmaceutical company, with a focused portfolio in core therapies. We are committed to improving the health and lives of people across the globe, through our broad research and development platform, and a growing late-stage pipeline. Working in over 100 countries, we have strength in emerging markets, and our medicines are used by millions of patients and clinicians worldwide.

Major Responsibilities:

  • Advise and answer queries from clinical study teams on implementation of AstraZeneca's genomics strategy and genetic informed consent (ICF), liaising with data privacy, clinical sample management, biobanks and other experts and functions as needed
  • Represent AstraZeneca's Centre for Genomics Research to investigators and clinical sites to inform and influence the appropriate application of genomics clinical sample science
  • Deliver and communicate end to end process map for genomics clinical science, including sample journey
  • Develop, maintain and deliver genomics clinical science documentation and training to support frequently asked questions from key stakeholders in the genomics clinical science process (e.g. for clinical sites, collaborations, principal investigators, etc)
  • Forecast and track genomic sample collection by AstraZeneca study teams and collaborators, including uptake of ICF by counties, sites and patients
  • Develop and maintain risk logs and mitigation strategies for the genomics clinical science process - e.g. flag need for amendments to clinical documentation or training
  • Check appropriate implementation of genetic protocol/ICF in studies

Qualifications, Skills and Experience Required:


  • Degree or equivalent experience in relevant subject
  • Good Clinical Practice training or equivalent experience
  • Delivery of large scale genomics clinical sample collection and logistics to facilitate exploratory research
  • Demonstrated ability to influence and persuade tactfully, to obtain desired outcomes while maintaining effective, positive, organizational relationships
  • Scientific background in genetics and genetic analysis, evidenced through publication record and external profile
  • Evidence of influencing clinical teams including both academic and industry partners for successful delivery of genomics research
  • Experience in clinical study operations including document preparation
  • Evidence of understanding and application of principles and guidelines for data privacy
  • Demonstrated leadership of process mapping and simplification
  • Excellent organization skills, attention to detail, written and oral communication skills


  • PhD or equivalent experience in relevant subject
  • Delivery of large scale, genomics clinical sample collection across different regions e.g. US, EU and Asia
  • Facilitating clinical sample collection and science for whole exome or genome sequencing
  • Experience of clinical study operations in pharmaceutical development across multiple therapy areas

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Apply now to join us and help us turn ideas into life-changing medicines.

Applications Open: 4th August 2017

Applications Close: 4th September 2017